In 1954 he published another memorable work, the " Atlas of Exfoliative Cytology ", thus creating the foundation of the modern medical specialty of cytopathology.
2.
Brush biopsy / exfoliative cytology is an alternative to incisional biopsy, where a stiff brush is scraped against the lining of the mouth to remove a sample of cells.
3.
In 1940, Isaza Mej�a examined the use of pituitrine in obstetrics in his work " Algunas consideraciones sobre el uso de la pituitrina en obstetricia " ( published by Antioquia, 1940 ) and founded the cytologic laboratory of the University Hospital of San Vicente de Pa�l in Medell�n, and introduced the exfoliative cytology in Colombia in 1949 . Mej�a wrote, among other things, an orientation and guidance for women and mothers : " Maternidad y menstruaci�n sin dolor : la educaci�n de los hijos " ( publisher Bedout, 1960 ).
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